However, dendritic cells (DCs), which rely on a specialized endocytic machinery that confers them the unique ability to “cross”-present antigens acquired by internalization, may use distinct MHC I ...

Based on these transcription factors, phagocytes expressing major histocompatibility complex (MHC) class II and integrin CD11c are named cDCs. Another independent subgroup, unconventional plasma-like ...

Dendritic cells (DCs) are professional antigen-presenting cells located in the skin, mucosa and lymphoid tissues. Their main function is to process antigens and present them to T cells to promote ...

Following skin transplantation, cutaneous dendritic cells ... graft APCs (bone marrow-derived MHC class II + cells) migrate to the draining lymph nodes of the recipient where they can activate ...

In summary, peripherally derived dendritic cells that infiltrate the CNS seem to be crucial for EAE development. Moreover, evidence is emerging that overproduction of particular cytokines by ...

However which bacteria confer benefit and mechanisms of action remain poorly defined. Dendritic cells, which are pivotal in early bacterial recognition, tolerance induction, and shaping of T cell ...

Tumor and dendritic cells. Tumor samples were processed within ... Before electrofusion, the MHC class I expression and ploidy of the tumor cells were determined by flow cytometry.

研究表明，胶质母细胞瘤（GBM）类器官是一个强大而准确的工具，可以了解我们用CAR-T细胞疗法治疗脑瘤时到底会发生什么。 孕期机体肠道微生物组 ...

1Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. 2Department of Surgery, Keio ...

The revised work remains incomplete due to remaining concerns about experimental methodology, cell health, and lack of dendritic Na-spikes which have been recorded in previous works. Non-linear ...

1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.