Dendritic cells (DCs) are professional antigen-presenting cells located in the skin, mucosa and lymphoid tissues. Their main function is to process antigens and present them to T cells to promote ...

Newly discovered brain cells count each bite before sending the order to cease eating a meal. Columbia scientists have found specialized neurons in the brains of mice that order the animals to ...

1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.

However, dendritic cells (DCs), which rely on a specialized endocytic machinery that confers them the unique ability to “cross”-present antigens acquired by internalization, may use distinct MHC I ...

Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Multiple sclerosis (MS) is considered to be a predominantly T-cell-mediated disease, and emerging evidence indicates that dendritic cells have a critical role in the initiation and progression of ...

Some of the most coveted areas for MHC investment are in the Sun Belt, particularly Florida, Arizona, Texas and New Mexico. Going forward, decreasing interest rates are expected to continue to ...

The closing of Fund II comes after the company secured a significant CMBS refinancing package for its Florida MHC portfolio. Citigroup provided a $65 million loan for 17 properties.

They provide convincing evidence for the effectiveness of IL-15/12-conditioned NK cells in this design, which was also critical for the authors being able to conclusively reveal the T cell-dependency ...

This valuable study provides solid in vivo data that transfer of IL-15/IL-12-conditioned syngeneic NK cells after primary tumor resection promotes long-term survival of mice with low metastatic burden ...

The endogenous MHC class I pathway is reserved for peptides ... Figure 1: Molecular mechanisms of licensing dendritic cells for classical cross-priming. Viral infections. Cross-priming is ...