In gene and cell therapy, RNP-mediated CRISPR gene editing is quickly emerging as the new norm. For many gene editing firms, GenScript has created hundreds of Cas9, Cas12a, Cas13a, MAD7 ...

but for viral gene variation within diversity-generating retroelements (DGRs) or for other diverse biological functions (e.g., CRISPR-RT). DGRs are critical for host adaptation in bacteriophages ...

CRISPR-Cas systems are prokaryotic immune systems ... the authors addressed this issue by adding polyaspartate tags to the termini of the Cas protein, enabling effective genome manipulation ...

The core components of CRISPR-based genome-editing therapies ... of mass spectrometry to identify and analyze the Cas9 and Cas 12 protein fragments recognized by immune cells.

These patterns are the basis of a primitive immune system that bacteria use to ‘remember’ the DNA of viral invaders by incorporating the DNA sequence of the virus within the CRISPR patterns. The Cas9 ...

The emergent field of CRISPR/Cas sensing technology is showing promise as a new paradigm in clinical diagnostics, although widespread clinical adoption remains limited. This perspective paper ...

Expanding Diversity in Economics+ (EDE+) brings together a diverse group of early undergraduate students to hone their research abilities and technical skills. EDE+ fosters a path toward a research ...

At Caterpillar, we believe diversity and inclusion (D&I) is a journey, not a destination. We are committed to continually working to ensure our workplace is diverse and representative of the many ...

Decades of research by scientists show that socially diverse groups—those with a diversity of race, ethnicity, gender and sexual orientation—display higher levels of innovation than homogeneous groups ...