Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...

A brief overview of the numerous proliferative activities directed by MYC is provided, along with examples of the genes responsible 138, in Table 1. This Timeline provides an opportunity not only ...