Ach, Acetylcholine; PACAP, Pituitary Adenylate Cyclase-Activating Peptide; AC, Adenylyl Cyclase; CA, Catecholamine ... The patterns of inter-adrenal cytokine regulatory effects on CA enzyme expression ...

This includes the situation where the decreased suppressive activity of an immune cell, such as T reg, results in an overall augmented immune effector function. By contrast, an activation of these ...

The dominant pathways through which IL-1β and IL-18 are believed to be elaborated are multimeric protein structures called inflammasomes that consist of sensor proteins, adaptor proteins and an ...

1 Department of Clinical Genetics, Addenbrooke’s Hospital, Cambridge, UK 2 Department of Medicine, University of Cambridge, Addenbrooke’s Hospital Correspondence to: Dr S M Park Department of Clinical ...

UM171 works by engaging with a protein called histone deacetylase (HDAC), which is part of a larger complex with CoREST, and gluing it to another protein named KBTBD4, which is an effector enzyme ...

SEATTLE, February 14, 2025--(BUSINESS WIRE)--Omeros Corporation (Nasdaq: OMER) today announced the availability on its website of materials accompanying two presentations given at the 2025 Tandem ...

In this study, the authors use the zebrafish to investigate how the microbiome affects a specialized gut cell called the lysosome rich enterocyte. They use a combination of functional assays for ...

SEATTLE--(BUSINESS WIRE)--Omeros Corporation (Nasdaq: OMER) today announced two presentations that will be featured at the 2025 Tandem Meetings – the Transplantation & Cellular Therapy Meetings ...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7365, United States ...