Their findings, published in Nature Communications, revealed significant variation in type VI secretion system (T6SS) effector genes, which enable nutrient uptake or bacterial ... Read more about ...

The dominant pathways through which IL-1β and IL-18 are believed to be elaborated are multimeric protein structures called inflammasomes that consist of sensor proteins, adaptor proteins and an ...

Department of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States ...

The work provides convincing evidence that multiple pancreatic islet cell types are key effector cell types. The authors also perform variant-to-gene mapping to nominate genes underlying several GWAS ...

Adenylyl cyclases (ACs) are crucial effector enzymes that transduce divergent signals from upstream receptor pathways and are responsible for catalyzing the conversion of ATP to cAMP. The ten AC ...

In this study, we investigated the effects of adenylyl cyclase (AC) signaling pathway modulation and different phosphodiesterase ... Blood samples were treated with the stimulators or inhibitors of ...

The Autoradiography core facility (ARG CF) is fully outfitted and staffed to support autoradiography (in vitro and ex vivo) and radioligand binding assays (whole cells or tissue homogenates) for ...