Enantiomer separation is a critical area of research in chemistry, particularly in the pharmaceutical industry, where the efficacy and safety of drugs can depend on the specific enantiomer used.
Enantiomers often differ in their involvement in the biological reactions in the body. An example is carvone, a compound found in both caraway seeds and spearmint. R-carvone gives a spicy aroma while ...
Chiral discrimination is a crucial aspect of chemistry, particularly in the pharmaceutical industry, where the efficacy and safety of drugs can depend on their chiral forms, or enantiomers.
Spatial arrangement of substituents having two mirror image (enantiomers) forms can exhibit different interactions with biological targets, leading to variations in their activity. Computational ...
In this review we provide a comprehensive overview of the utilization of macrocyclization in the optimization of kinase inhibitors by detailing the structural modification process from lead compounds ...
"In nature and in pharmacology there are multiple examples in which the two enantiomers have different ... out the UPV/EHU Professor of Organic Chemistry. This achievement addresses a current ...
Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom ...
However, chirality in these materials is typically fixed during their formation—once a crystal is grown, its left- and right-handed forms, or enantiomers, cannot be switched without melting ... no ...
Stratingh Institute for Chemistry, University of Groningen, 9747AG Groningen, The Netherlands ...
recruited from large global groups of desperate and unemployed people to work in closed compounds. Industrial-scale data collection and manipulation of victims worldwide. “But despite its large global ...