A new study reveals how AI-driven deep learning models can decode the genetic regulatory switches that define brain cell ...

A comprehensive analysis has identified novel enhancers associated with neuronal development and disease.

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

Zhang and his colleagues designed a generative AI model called ChromoGen to quickly ‘read’ DNA sequences and predict the ...

Stephen Scantlebury is facing the potential for a harsher penalty, after the brutal attack on a nurse at HCA Florida Palms ...

DNA 甲基化作为重要的表观遗传修饰，常发生在基因的启动子和增强子区域，能介导基因表达失调。一般来说，启动子或增强子区域的高甲基化会下调甚至使基因表达沉默；相反，低甲基化则倾向于上调甚至激活基因表达 。目前，虽有研究报道了某些特定基因甲基化对放疗后乳腺癌的影响，如 PRMT1 对 BRCA1 的甲基化可能激活暴露于电离辐射的乳腺癌细胞的 DNA ...

You may have never heard of harissa before, but this ingredient is actually one of the most popular in North African and ...

Thanks to the growing field of epigenetics, we're learning more about the interplay of genetic inheritance and environment in ...

In 1958, Francis Crick's sequence hypothesis finally provided an answer to the question: what is a gene? Why is this definition now considered overly simplistic? Roberts and Sharp also noted that ...