Buloxibutid is a first-in-class angiotensin II type 2 (AT2) receptor agonist that activates ... Approval and Priority Review. The Phase 2b ASPIRE trial to assess the safety and efficacy of ...
(G) Gastric adenocarcinoma, surgical resection from primary lesion. (H) Tumor cells show strong (3+) membrane staining (arrows) with FGFR2b. FGFR2b, fibroblast growth factor receptor 2 isoform IIIb; H ...
such as toll-like receptors (TLRs), Fc gamma receptors (FcγRs), and CD40L, which enable them to detect pathogens and participate in innate and adaptive immunity. MKs also phagocytose fungi and ...
announced today the successful completion of patient randomization for its Phase 2b OLIVE trial. The trial is investigating the efficacy and safety of BH-200, a potent vasopressin V1b receptor ...
The company is conducting two investigator-initiated clinical trials for its unmodified gamma-delta T cell product line – Phase 2b/3 pivotal trial for OmnImmune(R) in treatment of acute myeloid ...
We designed a molecule structurally unrelated to all FGFs, which potently mimicked basic FGF activity, by combining domains that (1) bind FGF receptors ... soluble FGFR–Fc fusion proteins ...
The binding affinity between two molecules can be determined using various methods. However, evaluating the Fc receptor interaction is typically achieved by SPR. This method preference can be ...