Neuroinflammation and immune environment play an important role in schizophrenia. Fc receptors can combine with antigen-antibody complex and transfer information into cells. In a post-mortem study, ...

E6F6-based immunotherapy facilitated the restoration of anti-HBV T-cell response in hydrodynamic injection (HDI)-based HBV carrier mice. Immunological analyses suggested that the Fcγ ...

Here we describe a mouse Fc receptor, designated Fcα/μR, and its human homolog, that bind both IgM and IgA with intermediate or high affinity. Fcα/μR is constitutively expressed on the ...

Eledon Pharmaceuticals has a promising anti-CD40L antibody for organ rejection prevention in transplantation. Learn more ...

Vaccine and natural immunity underlie the differences observed in Fcγ-receptor-binding (types I, IIa, and IIIa/b), IgG, IgM, and IgA production, and complement-fixing antibodies. Andrade ...

The latter consists of the phagocytosis of opsonized B-cells by neutrophils, monocytes and macrophages, which express the Fcγ Receptor. Moreover, RTX significantly decreases T-cell function, by ...

This medicine is designed to minimize binding to Fc-gamma (Fcγ) receptors on macrophages, helping the body’s immune cells detect, remain active longer and better fight tumors, while maintaining a ...

A sulfite allergy is caused by exposure to sulfur-based compounds naturally found in certain foods and used in certain food preservatives and additives. This can lead to allergy symptoms like wheezing ...

Whether IgG4 antibodies play any role apart from being a potential biomarker in CSS is unclear. Compared with the other IgG subclasses, IgG4 has a negligible ability to activate the classic complement ...

aDepartment of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China bDepartment of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China ...

In ITP, Octagam 10% rapidly increases the platelet counts. The mechanism is believed to involve Fc receptor blockade, which prevents antibody-opsonized platelets from being destroyed by Fc ...