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The basic mechanism of signal initiation is a stepwise process in which an agonist cytokine binds its cognate receptor. Together, this cytokine-receptor complex recruits an often-common secondary ...

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Introduction: We investigated the impact of rheumatoid arthritis (RA) associated cytokines and standard of care (SOC) RA therapeutics on immune checkpoint receptor (IR) expression on T cells to gain ...

Treatment is based on modifying the patient's own T cells to express artificial surface receptors to specifically recognize and attack the tumor cells. Objective: To synthesize available evidence on ...

China Universal Asset Management Co. Ltd. purchased a new stake in Sutro Biopharma, Inc. (NASDAQ:STRO – Free Report) in the 4th quarter, according to the company in its most recent 13F filing with the ...

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States Department of Molecular Biology and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital ...