A new study has revealed the existence of bifunctional diterpene cyclases/synthases (DCSs) in bacteria, offering compelling evidence that the plant terpene synthase gene family, termed TPS, originated ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

Conversely, mitochondrial fusion allows the mixing and exchange ... The authors identified a gene-expression signature associated with immune responses in the brains of mice lacking Parkin and ...

Whole genome sequencing can be an exceptionally valuable tool in cancer diagnostics. The application of this technique can ...

It combines an engineered compact prime editor for DNA modifications, a fusion activator for gene activation, and a multiplex array for producing tailored RNAs—all in one streamlined platform.

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

The new doors AI and machine learning are opening to scientists undoubtedly will invite weighty ethical and moral questions ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

He has been in minimal residual disease negative remission for 10 months after allo-HSCT. Result: His bone marrow karyotype showed a balanced translocation between chromosomes 8 and 17, leading to a ...