Reactivation of p53 Gene by MDM2 Inhibitors: A Novel Therapy for Cancer Treatment. Biomedicine and Pharmacotherapy. 2019. 109:484-492. Qin, J., Li, X., Hunt, C. et al. Natural Products Targeting the ...
Lampreys are jawless vertebrates that can offer unique insights into vertebrate evolution. Here they generate a comprehensive cell atlas of the lamprey, uncovering 70 distinct cell types across 14 ...
An in vivo base editing approach targeting the PRNP gene led to a 52% increase in the lifespan of mouse models inoculated with the most common sporadic and genetic types of human pathogenic prion ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...