Since their development in the mid-1990s, DNA microarrays have become a key tool in the fight against cancer. But just how do they help diagnose and treat patients?

Microarrays come in two basic flavours: complementary DNA (cDNA) or oligonucleotide arrays. cDNA arrays can be obtained commercially on filters, or made on glass slides. To compare mRNA levels in ...

In a microarray experiment the glass slide with the labeled DNA of interest plays a key role. As can be seen, a solid surface (in this example a glass microscope slide) contains thousands of spots.

Leading scientific journals require investigators carrying out DNA microarray research to deposit their data in an appropriate international database, [65] following a set of guidelines (MIAME ...

One way they do this is to use a DNA microarray to determine the expression levels of genes. When a gene is expressed in a cell, it generates messenger RNA (mRNA). Overexpressed genes generate ...

The late 1980s were heady days for molecular biologists. PCR was only a few years old. The automated DNA sequencer had just been invented. The Human Genome Project was being debated in Congress.

LuxScan 10K Microarray Scanner is a compact high performance system for microarray imaging and data analysis of DNA, protein and cell arrays. Its advanced systems for optics, signal processing and ...

Pat Brown, CEO of Impossible Foods (CA, USA) and professor emeritus in the department of biochemistry at Stanford University (CA, USA), takes us through the invention of DNA microarrays, their ...

Discovery of novel NTD candidate genes and expansion of clinical implications of others, with identification of four genes – RMND5A, HNRNPC, FOXD4, and RBBP4 – having strong potential involvement in ...

Bionano Genomics (BNGO) and Greenwood Genetic Center announced a publication in Genome Research describing the first study to use optical ...