We reason that these data indicate multiple functions of endogenous AnxA1, which become of relevance only after administration of the glucocorticoid. Collectively, this study reveals potent ...

In preliminary studies, we discovered that selected typical and atypical antipsychotic drugs interacted with virtually every biogenic amine receptor tested, in confirmation of many prior studies ...

As IKZF1 and BTG1 deletions are associated with a worse outcome in B-ALL, this study aimed to address whether they synergistically promote glucocorticoid resistance. Methods: Small interfering RNA was ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan ...

Introduction: Chimeric antigen receptor T (CAR-T) cell therapy is an innovative technology that has shown ... The regimen most used in the management of the syndrome included tocilizumab and/or ...