Recent research has highlighted the dual role of glutamate receptors in cancer, where they can act ... brain and plays a crucial role in cellular metabolism. Metabotropic Glutamate Receptors ...

The endocrine system, responsible for regulating physiological processes through hormone signaling, is intricately linked to nutritional metabolism, the process by which cells acquire and utilize ...

Studies have explored various proline analogs to identify effective inhibitors of PRODH, which is particularly relevant in cancer metabolism ... of proline to glutamate but also acts as a global ...

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Increasing gamma-aminobutyric acid (GABA) and balancing glutamate, brain chemicals called neurotransmitters, may help alleviate symptoms of fibromyalgia (FMS) and chronic fatigue syndrome (ME/CFS).

A brand new candidate for weight-loss treatment is on the table, with scientists uncovering for the first time how a hormone ...

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a ...

Fusobacterium nucleatum was notably abundant in OSCC tissues and actively participated in the conversion of L-glutamate to butyrate, a metabolite known to foster cancer cell proliferation.

Oct. 7, 2024 — Researchers discovered combining the brain-penetrating antipsychotic drug pimozide with a clinically investigative glutamine metabolism inhibitor, CB-839, can overcome tumor ...

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial ...

Gaining insights into cancer metabolism and genetics is essential for creating precise, targeted therapies that effectively combat cancer while preserving healthy cells. Information you provide will ...

Glutamate uptake is mainly accomplished by astrocytes which either convert glutamate to glutamine or feed it into their own metabolism. Normally, the astrocytic glutamate transporters are indirectly ...