It is classified as a first-generation H1 antihistamine and is primarily used for the treatment of allergies as well as motion sickness and nausea. First-generation H1 antihistamines like Benadryl ...

Hydroxyzine and Benadryl are both sedating antihistamines. They share many similarities but have different approved uses, ...

In the following section, the various methods used to evaluate antihistamines illustrate the developmental process for evaluating the efficacy of the H 1-receptor antagonist desloratadine.

Initial screening assays were performed with a large number of typical and atypical antipsychotic drugs. In preliminary studies, we discovered that selected typical and atypical antipsychotic ...

Benadryl‘s active ingredient is diphenhydramine, which works as an inverse agonist at the H1 receptor. This means it reduces allergic reaction symptoms by limiting the effects of histamine ...

This observation led Swedish investigators to propose, in 1948, that there are two types of receptors sensitive to histamine, and close to two decades later British researchers gave the name H1 to ...

However, even if you don't know what caused your child to break out in hives, the symptoms can be safely and effectively ...

This study revealed an association between elevated hepatic histamine levels and erythropoietic protoporphyria progression.

Despite concerns on the major neuropsychiatric side effects for long-term use of H1-receptor antagonist (anti-histamine, AH), one of the major therapeutic tools for allergic diseases, their ...

In vitro tests have demonstrated that second-generation antihistamines have improved H 1-receptor specificity and a slower dissociation rate compared with first-generation antihistamines ...