This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Specifically, ex vivo infection of AECs with RV, and biopsy specimens taken from children with ... analyses were performed using generalised linear analyses on log-transformed data to determine ...

You will be redirected to our submission process. This research topic focuses on the intricate interplay between the host immune response and potential therapeutic targets. Viral infections can ...

Study on Drosophilidae shows positive correlations in viral susceptibility, highlighting evolutionary trends that may predict ...

Interestingly, further evidence suggested that overexpression of IFITM3 could suppress vaccinia virus infection by interfering with virus-cell binding and low pH-dependent virus entry. This study ...

Active host-pathogen interactions take place during infection of human immunodeficiency virus type 1 (HIV-1). Outcomes of these interactions determine the efficiency of viral infection and ...

The feeling of fever is often accompanied by infection and is mainly caused by two infections: viral and bacterial. Both infections can lead to the patient experiencing similar symptoms but ...

Broad-Spectrum Antiviral NV-387 Phase II Clinical Trial Responding to MPox Pandemic in Africa, Readying to Tackle Bird Flu ...

What is a fever and what should I do if I get one? Get answers to common questions on the condition that impacts everyone ...

Using mouse infection models, researchers demonstrated that disrupting the Mce3C-CTSB interface promotes host apoptosis while suppressing necroptosis, leading to attenuated Mtb survival and ...

However, despite extensive studies on IgM as an ancient antiviral weapon in warm-blooded vertebrates, its role and mechanisms in combating viral infections in early vertebrates remain poorly ...