JAK/STAT, and T-bet. In PD-1/PD-L1 immune checkpoint inhibitor cancer treatment, IFN-γ is a prognostic marker. The production of IFN-γ is associated with an improved response to immune ...

IFN-γ signals through the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway, playing a key role in both innate and adaptive immunity. It enhances ...

"Our results indicate that interferon-alpha-1 and interferon ... the one known as the JAK-STAT pathway, analyzed in the new study, is one of the most direct routes. The team was able to develop ...