近日，复旦大学附属中山医院的葛均波、吴鸿谊和赵刚等人在《Life Metabolism》期刊上发表了一篇题为《间歇性禁食通过肠道代谢物吲哚-3-丙酸抑制血小板激活和血栓形成》的研究论文。该研究结合人类和小鼠模型，揭示了间歇性禁食对心血管系统的保护作用及其背后的生物学机制。 研究人员发现，间歇性禁食可以通过提升肠道菌群代谢物——吲哚-3-丙酸（IPA）的水平，抑制血小板激活和血栓形成，从而对心血管疾 ...

Indole also enhances the production of inflammatory antibodies, worsening immune system attacks on the joints. Understanding ...

is a compound derived from the chemical indole-3-carbinol found in cruciferous vegetables like broccoli and Brussels sprouts. DIM plays a role in estrogen metabolism and has been studied for its ...

Tryptophan 2,3-dioxygenase (TDO), as a key rate-limiting enzyme, is widely involved in tryptophan metabolism and the regulation of various physiological and pathological processes. TDO activity can be ...

Study: Intermittent fasting inhibits platelet activation and thrombosis through the intestinal metabolite indole-3-propionate ... published in the journal Life Metabolism determines the effect ...