Carbapenem-resistant Enterobacterales (CRE), including carbapenem-resistant Klebsiella pneumoniae and carbapenem-resistant Escherichia coli, pose a major risk to patients and healthcare systems in the ...

A study reveals alarming rates of antibiotic resistance in Gram-negative bacteria, highlighting the urgent need for ...

pneumoniae: Klebsiella pneumoniae, M. tuberculosis ... a MTB-specific insertion sequence presents 6–10 times per genome. The CRISPR-MTB test showed a greater sensitivity over both culture and Xpert ...

Overuse of antibiotics is the main cause of the so-called “silent pandemic” of AMR infections, with a type of infection called Klebsiella pneumoniae now becoming a major issue for hospitals ...

CAMBRIDGE, MA AND PITTSBURGH, PA / ACCESS Newswire / February 10, 2025 / Next Gen Diagnostics (NGD), a pioneer in the development of machine learning models for whole genome sequence- (WGS-) based det ...

Pneumonia symptoms can vary based on the cause and severity of the lung infection. For some, it might feel similar to the flu or be barely noticeable. For others, pneumonia can cause severe ...

Structural variants in the human genome include cytogenetically detectable and submicroscopic deletions, duplications, large-scale copy-number variants, inversions and translocations. The ability ...

Objective To predict the cost and health effects of routine use of whole-genome sequencing (WGS) of bacterial pathogens compared with those of standard of care. Design Budget impact analysis was ...

Bacterial insertion sequences (IS) are small DNA segments (<2.5 kb) with a simple genetic organization. Most IS elements exhibit short terminal inverted repeat sequences (IR) and encode a transposase, ...

同时，研究还比较了肺癌肿瘤组织和配对血浆样本的微生物谱。虽然肿瘤组织中的微生物物种数量和多样性低于血浆，但 13 个共有的核心微生物物种中有 10 个在两者之间没有差异，这表明肿瘤内微生物组可能是循环微生物核酸的来源之一，但这一结论还需要进一步研究来证实。

Aug. 6, 2024 — An AI-based analysis of over 2 million hospital visits has found that most of the time, a pneumonia diagnosis made in the hospital will change from a patient's entrance to their ...