The odds ratio for exposure to L-dopa in the IPD patients with PN was 12.4 (95% confidence interval, 1.4–109.1). There were no differences between the groups in the use of other PD drugs ...

We simultaneously recorded local field potentials (LFPs) in the primary motor cortex and dorsolateral striatum in order to study L-DOPA-induced dyskinesia in 6-OHDA lesioned hemi-parkinsonian rats.

Administering the drug levodopa (L-DOPA), which is converted into dopamine in the brain, can help to counter disease-associated dopamine loss. However, over a number of years, the brain of a ...

Department of Chemistry, Chungnam National University, Daejeon 34134, Republic of Korea ...

Treatment of PD with L-DOPA or dopamine receptor agonists effectively reduces motor deficits ... In a similar model, we identified important changes in sleep architecture and micro-structure, ...

In a previous mechanistic study using single-molecule atomic force microscopy (AFM), Messersmith and colleagues 4 showed the versatility of adsorbed DOPA on ... mechanism and structure of the ...

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Instrument Authorized Capital Issued Capital - P A I D U P - ...

Correspondence to Dr Ryuji Kaji, Department of Neurology, Tokushima University, Tokushima 770-8503, Japan; rkaji{at}clin.med.tokushima-u.ac.jp ...

Peroxynitrite induces cell death, and can influence signal-transduction processes, mitochondrial function and signalling of apoptosis. The formation and reactions of peroxynitrite play a ...