This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

In general, chemotherapy medications work by attacking cells or by preventing them from growing and dividing. Cancer cells tend to grow and divide rapidly and uncontrollably, and many chemotherapy ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...

What Is an Inflamed Liver? Inflammation is the body's way to heal an injury or damaged cells. In the liver, this injury can be caused by many things, including an infection, toxins, or the buildup ...

“These viruses can cause cell death, and chronic infections can lead to scarring, or fibrosis,” says Sudha Kodali, MD, a hepatologist in Sugar Land, Texas, and a volunteer for the American ...

Methods The fibrotic specimens of patients and HLF (hepatic leukemia factor) PB/PB mice were used to assess the expression and role of HLF in liver fibrosis. Primary murine hepatic stellate cells ...

1Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, P. R. China. 2Jiangsu Key Laboratory ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

In 2020, the Takemori group at Ehime University originally developed PEPPI-MS, an innovative method for high-resolution fractionation ... analysis of human cultured cells via top-down proteomics ...

Akero Therapeutics reported Monday strong results from a nearly two-year, placebo-controlled study showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused by the ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. The specific functions of these cells in the context of ...