The role of the IL-33–ST2–CXCL3–CXCR2 axis in PDAC metastasis was evaluated in three clinically relevant mouse PDAC models. Results IL-33 was specifically elevated in human PDACs and positively ...

Glioma is a malignant tumor of the central nervous system (CNS). Currently, effective treatment options for gliomas are still lacking. Neutrophils, as an important member of the tumor microenvironment ...

Integrated density for each band was measured using ImageJ software. Neutrophils were pre-treated with the CXCR2 receptor antagonist AZD5069 (Cayman Chemical), the TGF-β1 receptor ALK5 antagonist ...