Here the authors show that, in mouse tumors, CD8 + T cells with a low-avidity TCR are the mediators of antitumor and immunotherapy responses, in part because T cells with a high-avidity TCR are ...

T-cell lymphoma is a type of lymphatic cancer that starts in the T lymphocytes (T cells), a type of white blood cell. T lymphocytes (T cells) and B lymphocytes (B cells) are two types of white blood ...

Copyright: © 2025 Elsevier Ltd. Published by Elsevier Ltd. CAR T-cell therapies have revolutionised treatment of many diseases, but their expense means many patients ...

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some ...

While naïve T cells lacked the disease-fighting imprinting of memory cells, they became more effective when RUNX2 was added. They also lived longer and the gene protected them against exhaustion ...

The best T-Mobile cell phone plans give you access to unlimited data each month. But the question you need to answer when you have to pick a T-Mobile plan is which of T-Mobile's several unlimited ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

antitumor response elicitation and promoting the migration of T cells to the immunization site [36] ES-DC transfected with OVA + CCL21 OVA-expressing melanoma MO4 cells The most effective in ...

1Division of Cancer Biology, Aichi Cancer Center Research Institute, Nagoya, Japan. 2Department of Respiratory Medicine, Fujita Health University School of Medicine, Toyoake, Japan.