A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types." ...

A new study draws a line between random genetic mutations and predictable epigenetic changes used to measure biological aging ...

Figure 1. The mechanism of DNA methylation. The methyl groups are transferred from the S-adenosine-L-methionine (SAM) molecule to the position of cytosine C5 under the action of methyltransferase, ...

DNA methylation is the most widely studied and best characterized epigenetic mechanism (16). It involves the covalent attachment of a methyl group to the fifth carbon position of a cytosine nucleotide ...

DNA and RNA epigenetics, once thought to be separate, have now been found to work together to fine-tune gene expression.

Life X DNA, a leader in advanced DNA health testing, offers rapid methylation testing in New Zealand, providing residents with easy access to high-grade at-home DNA tests. With growing interest in ...

Mapping DNA methylomes in single cells is challenging, and thus studies using bulk samples remain common. Here, authors develop a transformer-based method for methylation pattern analysis to ...

Our results suggest that forensic applications of DNAm clocks using non-blood tissue types will provide age estimates that are not as accurate as ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Here, we aimed to explore the precancerous nature of IM by analysing epigenetic alterations. Design Genome-wide DNA methylation analysis was conducted by EPIC BeadArray using IM crypts isolated by ...

However, how DNA methylation leads to gene silencing remains poorly understood. Candidates for facilitating DNA methylation-dependent gene silencing include proteins predicted to recognize methylated ...