Researchers at the University of Cologne and University Hospital Cologne have determined that the novel mRNA-based COVID-19 ...

(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common DEGs up- or down-regulated across the six scRNA-seq datasets (NC vs.

Researchers at the University of Cologne and University Hospital Cologne have shown in their study that the novel mRNA-based ...

Selectively inactivating a molecular switch that turns on the gene Nr4a1 in monocytes but not macrophages leads to the loss of patrolling monocytes, which play an important role in suppressing ...

Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse ...

The monocyte effect. Monocytes/macrophages (promonocytes in the bone marrow, circulating monocytes, tissue macrophages) play a major role in the induction and regulation of immune reactivity.

Our expertise includes the isolation and culture of primary human and rodent cells (lymphocytes, monocyte/macrophages, and other immune cells; fibroblast-like synoviocytes; myoblasts), functional ...

Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...

When they administered the modified macrophages into the lungs of mice via the trachea, they saw reduced inflammation caused by hypoxia, and monocyte recruitment was halted. Four weeks after ...