No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

A combination of single molecule, biophysical and biochemical ... The fraction of the ATPase cycle time that a myosin spends strongly bound to an actin filament is known as the duty ratio.

The image shows, top, a 3D visualization of the shutdown state of the myosin molecule, where the tail has wrapped around the head; below that is a myosin molecule in its active state and at the ...