In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

2019). Microtubules are associated with peripheral actin/myosin-enriched lamellae, and they are the scaffold for the unidirectional transport of macropinosomes. Critically, inhibitors of microtubule ...

Since cancer is a multifactorial disease, it has become necessary to develop new molecular therapies that can target several relevant cellular processes at once. Ion channels are versatile regulators ...

It seeks to understand the process of trait inheritance from parents to offspring, including the molecular structure and function of genes, gene behaviour in the context of a cell or organism (e.g ...

Validated by morphological studies after identification by mass spectrometry. As the molecular mechanisms underlying zymogen granule (ZG) formation, the sorting/packaging of cargo and regulated ...