Resistance to apoptosis, therefore, is probably a principal mechanism whereby tumors are able to overcome these cancer therapies. The transcription factor NF-κB is activated by chemotherapy and ...

In a new study, researchers have determined that a protein called NF-kB c-Rel can intensify the symptoms of psoriasis when activated by signals from the body's immune system. Understanding how 'c-Rel' ...

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

Apoptosis: The process of programmed cell death ... when a blood vessel supplying blood to the brain is obstructed. NF-kB pathway: A signaling pathway that plays a crucial role in regulating ...

Z526- a novel dithiocarbamate-like compound reverses cancer associated cachexia via mitigating NF-B signaling and oxidative ...