It is a long-standing question in the field why simple NMDA receptor activation by bath application of NMDA does not induce LTP, but instead induce LTD. Rab proteins are regulated by many GEFs and ...

N-methyl-D-aspartate (NMDA) receptors are critical for higher-order nervous system function, but in previously published protocols to convert human induced pluripotent stem cells (iPSCs) to mature ...

1月16日，团队在Cell杂志上首次以原子分辨率呈现出了内源NMDA受体的组装和结构；2月25日，上线Neuron杂志的论文揭示了镁离子调控NMDA受体的分子机制；3月5日，团队联合中国科学院上海药物研究所李扬/郭飞研究组在Science Advances杂志上证实了GluN2D亚型NMDA受体可成为快速抗抑郁药物的新靶点。

They pinpointed differences in long-term potentiation, a sustained strengthening ... levels how GLDC functions as a novel regulator of NMDA receptors," Rudolph said. "Dysfunction of NMDA receptors ...

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They pinpointed differences in long-term potentiation, a sustained strengthening ... of glycine was indeed sufficient to inhibit the NMDA receptors' function and was involved in the schizophrenia ...

LTP’s Hong Kong subsidiary, LiquidityTech Limited (LTP HK), has obtained five operational licenses from the country's Securities and Futures Commission (SFC), expanding its regulated services ...

Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative affect, and ...

星形胶质细胞吞噬作用对皮质纹状体突触可塑性的需求：研究人员利用光遗传学方法在控制组和 DAPS 小鼠脑片的皮质传入纤维中诱导 θ 波爆发刺激（TBS），观察皮质纹状体长时程增强（LTP）。结果显示，控制组中 TBS 能诱导 N - 甲基 - D - 天冬氨酸（NMDA）受体依赖 ...