Brief pain inventory; LANSS: Leeds assessment of neuropathic symptoms and signs; MPQ: McGill pain questionnaire; NPS: Neuropathic pain scale; NRS: Numerical rating scale; VAS: Visual analog score.

With FDA fast track and breakthrough therapy designations already secured for the drug to treat acute pain, Vertex is now focusing on neuropathic ... numeric pain rating scale (NPRS) assessed ...

which compared AP-325 to placebo in people with post-surgical neuropathic pain, the drug achieved a significant and "clinically meaningful" reduction in the Pain Intensity Numeric Rating Scale (PI ...

Vertex Pharma's non-opioid painkiller suzetrigine was unable to perform better than placebo in a phase 2 trial in lumbosacral radiculopathy (LSR), a form of neuropathic back pain, ahead of an FDA ...

(1) “Efficacy and Safety of ATX01 in Adult Patients With CIPN (Chemotherapy-induced Peripheral Neuropathy) (ACT)”. The purpose of this clinical trial is to compare the efficacy of twice daily ...

They enrolled 36 patients with unilateral chronic neuropathic pain that ... A patient's pain was rated on a visual analog scale ranging from 0 to 100. All rTMS sessions significantly relieved ...

Allosteric GABA A-receptor modulator AP-325 showed rapid onset as well as long-lasting pain reduction in patients with chronic neuropathic ... Numeric Rating Scale (PI-NRS) within less than ...