These findings are all in keeping with the known NF1 phenotype. Macrocephaly is reported to correlate with optic pathway gliomas in approximately 62% of children with NF1 (Schindera et al., 2011); ...

A study, published in Cancer Cell, shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United ...

Mar. 13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States ...

Correspondence to: Professor Ian R Whittle Department of Clinical Neuroscience, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK; irwskull.dcn.ed.ac.uk ...

Researchers have developed a high-speed electro-optic switch that is energy-efficient, has low crosstalk and works across a broad bandwidth. Made using a scalable, chip-friendly process ...

Size and structure should be assessed, especially proximity to the optic chiasm. Laboratory evaluation with a serum prolactin for small tumors is cost effective, other lab testing is indicated if ...

Medical treatment is initially based upon the use of corticosteroids to treat the inflammatory process. Ordinarily, this is given in the form of high-dose prednisone or equivalent steroids ...