In addition to these decisions, which are made in the G1 phase of the cell cycle, checkpoints that operate ... but many of these signals feed into the p53 pathway.

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

One group showed that p53 controlled the progression of the cell cycle, but it wasn’t clear how. 24 Guillermina Lozano entered the p53 field as a postdoctoral fellow in Levine’s lab in 1985 and ...

The aim of the present work was to establish an association between wood smoke exposure and lung cancer pathogenesis, and to analyze the effects of wood smoke on p53 and murine double minute 2 ...