Alternately, if the mutation has a positive affect on the fitness of the offspring, it is called an adaptation. Thus, all mutations that affect the fitness of future generations are agents of ...

Negative (and positive) selection in such a system never ... If negative selection is too weak to remove harmful mutations, then deleterious mutation accumulation will occur, and a gradual decay ...

The former NBC news anchor, 49, revealed last month in an Instagram post that she had tested positive for the BRCA1 gene mutation, putting her at a higher risk for breast and ovarian cancer.

thankfully — the mutations were similar to those found in a teenager who tested positive for the virus in Canada in November. When the news broke, Dr. Angela Rasmussen, a virologist at the ...

For years, breast cancer treatment has been guided by genetic alterations found in tumor tissue, typically through invasive biopsies.

This treatment effect was statistically significant ( p=0.01) in all subjects, regardless of mutation at two years, validating the gene-agnostic mechanism of action for OCU400. This data ...

The appraisal committee has prepared final draft guidance (FDG) on olaparib for treating BRCA mutation-positive HER2-negative metastatic breast cancer after chemotherapy (Review of TA762) [ID6336] and ...

Pfizer has announced that its Braftovi (encorafenib) regimen significantly improved both progression-free and overall survival in a late-stage colorectal cancer (CRC) study.