This important study characterizes and validates a new activity marker - fast labelling of engram neurons (FLEN) - which is transiently active and driven by cFos, allowing the monitoring of intrinsic ...

A snake catcher in Australia discovered a "dangerously venomous" eastern brown snake inside an Australian family's washing machine earlier this month.

This study by Bell et al. focuses on understanding the roles of two alternatively spliced exons in the single Drosophila Cav2 gene cac. The authors generate a series of cac alleles in which one or the ...

Intra-Cellular Therapies' CAPLYTA is making waves in the antipsychotic market, gaining traction as a novel treatment for schizophrenia and bipolar de ...

Ion channels are integral membrane protein assemblies that modulate the flow of ions into and out of a cell or organelle, leading to generation of electrical signals. Opening (gating) of ion ...

More information: Hermany Munguba et al, Projection-targeted photopharmacology reveals distinct anxiolytic roles for presynaptic mGluR2 in prefrontal- and insula-amygdala synapses, Neuron (2025).

Disturbed sleep is a prominent feature of fibromyalgia symptomatology and has been proposed as one of the core symptoms that should be systematically assessed in clinical trials for the treatment ...

好书推荐！《动物行为实验指南》电子版pdf，网盘发货《动物行为实验指南》共674页，涵盖了常见的实验动物，如小鼠、大鼠和斑马鱼，详细描述了每一种行为测试的实验设计、测试设备、实验流程、评估指标、预期结果、常见问题及解决方法、数据分析、模型应用与局限性等各个方面。它通过快速引导，帮助研究人员高效地掌握实验的 ...

The addition of β-adrenergic antagonists to the treatment regimen for heart failure has validated the neurohormonal hypothesis and provided much-improved outcomes. This benefit had been in ...

Synaptic plasticity is the biological process by which specific patterns of synaptic activity result in changes in synaptic strength and is thought to contribute to learning and memory. Both pre ...

Projection-targeted photopharmacology reveals distinct anxiolytic roles for presynaptic mGluR2 in prefrontal- and insula-amygdala synapses. Neuron , 2025; DOI: 10.1016/j.neuron.2025.01.002 Cite ...