Amyloid was then subclassified by immunohistochemistry. LCDD was diagnosed if renal biopsy showed non– Congophilic, light chain–restricted deposits that were granular by electron microscopy.

Previously known as primary amyloidosis, systemic amyloid light chain (AL) amyloidosis is the ... This type is an autosomal dominant disease in which the genetically inherited variant form of ...

These findings not only offer novel insights into LC structural dynamics but also hold promise for guiding therapeutic strategies in amyloidosis and will be of particular interest to structural ...

Dysphagia is an uncommon presentation of systemic immunoglobulin light-chain (AL) amyloidosis with multiple myeloma (MM ... Oesophagogastroduodenoscopy showed ulcerations of oesophagus and duodenum.

Amyloidosis is a disease complex characterized by the deposition of protein fibrils in various organs ... Cardiac involvement has been predominantly noted in amyloid light chain (AL) amyloidosis (also ...

Lichenoid amyloidosis (LA), a subtype of primary cutaneous amyloidosis (PCA), is featured by intensely pruritic, hyperkeratotic papules which lacks standardized treatment. Dupilumab, a human ...

RASI appeared to have a direct correlation with left ventricular mass index in patients with AL-CM but not in patients with ATTR-CM The relative apical sparing index (RASI) appears to accurately ...

AstraZeneca has clearly made the rare disease transthyretin amyloidosis ... last year for another form of the amyloidosis known as amyloid light chain (AL) amyloidosis in a $500 million deal.