By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage.

Methods: We performed immunostaining on human skin and peripheral blood mononuclear cells (PBMCs) and visualized primary cilium. Result and discussion: We show that human dendritic cells (DCs) and LCs ...

Though much progress has been made in recent years towards understanding the function and physiology of primary cilia, they remain a somewhat elusive organelle. Some studies have explored the role of ...

Many cells in our body have a single primary cilium ... the organelles when a visitor to the lab pointed out cilia in 3D images of mouse brain tissue. She was captivated by the ability to see ...

and Harvard Medical School used super high-resolution 3D electron microscopy images of mouse brain tissue generated for creating connectomes to get the best look yet at primary cilia. Their ...

Distal appendages are nine-fold symmetric blade-like structures attached to the distal end of the mother centriole. These structures are critical for formation of the primary cilium, by regulating at ...

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