Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

To understand how Bil works, Sorek’s team compared phage progeny from infected bacteria with and without the system. They performed density gradient centrifugation to separate phages from bacterial ...

[1] In addition to permanently shutting down bacterial metabolism, lysis also releases phage progeny into the surrounding environment, allowing them to infect similar bacteria found nearby.

"If we understand the defense mechanisms activated by the bacteria in response to phage infections, we can develop methods to bypass them." For the study, the researchers selected the bacterium ...

Researchers have been investigating how these single-celled organisms withstand phage infections to gain ... the invader that is passed on to their progeny as the bacteria reproduce.