Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study.

The University of Michigan has synthesized proteolysis targeting chimeras (PROTACs) comprising a von Hippel-Lindau disease tumor suppressor (VHL)-binding moiety coupled to a signal transducer and ...

Son of sevenless homolog 1 (SOS1) is an essential guanine nucleotide exchange factor (GEF) in KRAS-driven tumors, and it also functions as a downstream node protein of BCR-ABL, suggesting its critical ...

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do ...

Delve into the increasingly dynamic landscape of ALS treatment development with thirteen companies advancing candidates in ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...

After treating a tumour with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the ageing process and are resistant to cell ...

A new study describes a molecular mechanism that could drive the design of strategies to eliminate senescent cells in cancer ...

Biochemistry is the study of the structure and function of biological molecules such as proteins, nucleic acids, carbohydrates and lipids. Biochemistry is also used to describe techniques suited ...

背根神经节（DRG）起源于神经嵴，负责传递感觉信息。近日，我国科学家在《Cell》（IF：45.5）发表研究成果，深入解析人类背根神经节中感觉神经元的发育过程，通过构建人类胚胎DRG的单细胞时空转录组图谱和人类DRG类器官模型，增强对感觉神经元多样化的分子机制的理解，也为研究感觉神经元的分化和功能提供新的实验平台。

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The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology, the journal has an international reputation for quality and originality. The ...