Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Strategies for delivering nucleic acids into damaged and diseased tissues have been divided into two major areas: viral and non-viral gene therapy. In this mini-review article we discuss the ...

Their ability to incorporate therapeutic and diagnostic agents is nowhere more demanding than the attempts to employ nucleic acid-based agents, so called gene medicines. Nucleic acids provide ...

Nanoscope Therapeutics is on the brink of filing for FDA approval of what could be the first gene therapy for incurable eye disease retinitis pigmentosa (RP) that can be used regardless of ...

Orchard Therapeutics to Receive WORLDSymposium™ New Treatment Award ...

We quantified the frequency of HSV reactivations in highly active antiretroviral therapy (HAART)-treated adults with HIV, and compared it with that in HAART-naïve patients. Setting 2 academic hospital ...

This will still allow a substantial amount of virus replication that, with the selective pressure from antiretroviral therapy, will allow resistant viruses to emerge rapidly. With more intensive ...

Gene expression is the generation of a functional ... Here, the authors identify ancient endogenous retrovirus THE1B fusion transcripts that are aberrantly expressed in sarcoidosis.

Murine hematopoietic cells were transduced with ecotropic supernatants (Figure 1b), using conditions that led to efficient gene marking with low provirus copies (<3) per cell. 23 Polyclonal ...

2024 — Researchers have shown unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy ...

A Readily Available Dietary Supplement May Reverse Organ Damage Caused by HIV and Antiretroviral Therapy Mar. 24, 2023 — MitoQ, a mitochondrial antioxidant that is available to the public as a ...

Antiretroviral therapy is the standard HIV treatment, but patients are never rid of the virus. A new study raises the possibility of HIV elimination through gene-editing with CRISPR.