In this context, we will provide a summary of recent research findings on how PD-related proteins affect mitochondrial functions through SUMOylation, acetylation, or s-nitrosylation, to elucidate ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...

Results from three biological isolates per genotype are graphed. (E) Mec1 is required for Srs2 sumoylation. Experiments were performed and data are presented as in panel A. Figure 6. Mec1 and RPA ...

Furthermore, E1B-55K has been shown to interact with other viral proteins, such as E4orf6, which can inhibit its SUMOylation—a post-translational modification that affects protein function and ...

coli-induced senescence and tumour growth. The mechanism underlying colibactin-induced senescence involves microRNA-20a-5p, which targets SENP1, a key protein in the regulation of p53 SUMOylation. The ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

G6PD expression can be abnormally elevated in a variety of cancers. In addition, G6PD may act as a regulator of viral replication and vascular smooth muscle function. Therefore, G6PD-mediated ...

The liver performs hundreds of vital functions, including converting nutrients from food into energy, filtering toxins from the blood, and producing bile, a key substance in digestion and waste ...

As a result of these alterations, proteins encoded by the same genetic sequence often diverge in function. Researchers have begun to get the lay of the ... And when SUMO (small ubiquitin-like modifier ...

Wintering Monarch butterflies (Danaus plexippus), Santa Cruz, California. Masses of migrants gather in eucalyptus groves to overwinter before returning north; their numbers have decreased as a ...