为探究蝙蝠细胞对 SARS-CoV-2 复制产生的双链 RNA(dsRNA)的反应,研究人员开展相关研究,发现 Dicer 参与限制病毒复制,对理解蝙蝠抗病毒机制及相关疾病治疗有重要意义。 蝙蝠与 SARS-CoV-2 的奇妙 “共处” 之秘:Dicer 的独特作用 在大自然的病毒 “库藏” 中 ...
本研究聚焦于解决泰国曼谷在全面开放后如何有效监测和预警新冠感染问题。研究人员通过废水流行病学(WBE)技术,对曼谷10个污水处理厂的200份废水样本进行SARS-CoV-2 RNA检测与分析,揭示了废水中的病毒RNA浓度与官方报告病例数的显著相关性,并成功预测了 ...
Background Infectious agents such as SARS-CoV-2 require strategies to contain outbreaks, particularly in hospitals where the ...
研究团队发现了一种名为CIM-834的小分子化合物,它能够有效抑制SARS-CoV-2和SARS-CoV的组装。CIM-834通过阻止冠状病毒膜蛋白(M蛋白)从短形式(Mshort)向长形式(Mlong)的构象转换,从而阻止病毒颗粒的组装。该化合物在 ...
还是后处理(先SARS-CoV-2感染,后药物处理),这三种药物均能显著降低病毒RNA水平。同时三种药物以剂量依赖的方式降低了β-半乳糖苷酶活性(图3 ...
 "The SARS-CoV-2 virus uses RNA, instead of DNA, to store its genetic information. Our lab has long been interested in studying RNA biology, and when SARS-CoV-2 emerged we decided to investigate ...
The Remarkable and Mysterious Coronavirus Genome The SARS-CoV-2 genome is a strand of RNA that is about 29,900 bases long--near the limit for RNA viruses. Influenza has about 13,500 bases ...
This is SARS-CoV-2, the virus that causes COVID-19. It's a type of RNA virus, some of which mutate practically every time they replicate. SARS-CoV-2 is actually one of the rare RNA viruses that ...
T he rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many ...
The following is a summary of “A viro-immunological model to characterize the antiviral effect of molnupiravir in SARS-CoV-2-infected outpatients: implication for treatment duration,” published in the ...
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