To determine the pathways that regulate primary human sebocytes growth and differentiation, we developed a novel culture method by mimicking the microenvironment of the sebaceous glands in vitro.

Meibomian gland dysfunction (MGD ... expression of hyperkeratinization markers and cell proliferation or stimulated Raman scattering (SRS) microscopy to assess lipid quality.

But while health care providers can now successfully develop drugs that use dsRNA to accurately target and silence disease-causing genes ... RNA molecules into cells efficiently.

Figure 1: Transgene expression and phenotype. Figure 2: K14.MYC2 mice exhibit impairment in wound healing. Figure 3: K14.MYC2 primary keratinocytes exhibit a defect in migration. Figure 4: K14 ...

In 2020, we wrote about why there were only 11 cell and gene therapies in Europe. A bit over four years later, there are 20 – almost twice as many. But is it such a big improvement? Take a look ...

The white capsule drug approaches DNA and cells to release the therapeutic agent. A living cell medicine, developed by genome editing, that acts directly on the affected area. gene markers stock ...

Igraph and Circlize softwares were employed to show the networks of cell‐to‐cell communication. These results revealed that the murine adrenal gland microenvironment was highly heterogeneous and ...

Violin plot was used to show the distribution of differentially expressed genes ... cells were highlighted and dissected to characterise the composition and proportion. Results Cell types in each ...

By knocking out a gene circuit responsible for producing lactic acid -- a metabolite that makes the cells' environment toxic -- researchers eliminate a primary hurdle in developing cells that can ...

Design We determined the distribution of gastric gland cell lineages with specific immunocytochemical markers in entire stomach specimens from three non-obese organ donors. Results The anatomical body ...

Tissue-resident immune cells reside in distinct niches across organs, where they contribute to tissue homeostasis and rapidly respond to perturbations in the local microenvironment. Innate lymphoid ...