Background Trimethoprim-sulfamethoxazole (TMP-SMX) is a commonly used antibiotic for the treatment of skin and soft tissue infections, with good bactericidal effect on gram-positive cocci and ...

untested agents such as trimethoprim–sulfamethoxazole or clindamycin are often being used. Thus, topical approaches may offer effective, localized, well-tolerated alternatives to the systemic ...

1 First Department of Infectious Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China 2 Department of Infectious Diseases, The First Affiliated Hospital of Xiamen ...

Bacterial insertion sequences (IS) are small DNA segments (<2.5 kb) with a simple genetic organization. Most IS elements exhibit short terminal inverted repeat sequences (IR) and encode a transposase, ...

When you first enter a new world, you can either spawn near a structure or find one while exploring any of the three dimensions. While finding some can be quite easy, others are extremely hard to ...

The team believes that the structure was in use until the 8th century BCE, the middle of the period when the Kings of Judah ruled. A scarab seal from the 8th century BCE uncovered during the ...

A search was conducted to find clinical trials of topical antimicrobials for uSSSI. The MEDLINE database was searched for articles from 1966 through to August 2007 using the subject terms 'topical ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...