We then, extended these physiological findings to include characterization of sleep-need related differential expression of glutamatergic synaptic shaping genes that can control the observed ...

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Activating excitatory neurons significantly promoted functional recovery and inhibited microglia-mediated synaptic pruning after stroke. Furthermore, it decreased EPS and C1q levels in synapses. On ...

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Scientists have pinpointed a brain circuit that, when activated, reduces anxiety without impairing memory. Using ...

Somatostatin-expressing neurons of the entopeduncular nucleus (EPNSst+) provide a limbic output of the basal ganglia and co-release GABA and Glutamate in their projection to the lateral habenula, a ...

Some common neurotransmitters in the brain and body include serotonin, dopamine, glutamate ... At the end of each neuron is a tiny gap called a synapse, and to communicate with the next cell ...

Most excitatory synapses use the neurotransmitter L-glutamate, which activates specific receptor channels in the postsynaptic ... Around the cell's resting potential the block is in place; upon ...

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears ...