This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism—a novel genomically recoded organism ...

According to earlier reports, synonymous substitutions were considered phenotypically silent; thus, such mutations were frequently ignored in studies of viral mutations because they did not directly ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

Synthetic biologists from Yale were recode the genetic code of an organism, a novel genomically recoded organism (GRO) with ...

A less-virulent poliovirus generated by altering codon usage suggests a new strategy for vaccine development. Figure 1: Development of an attenuated vaccine by two classical methods and the ...

RNA technology is an emerging field that exploits the unique structural and functional properties of RNA to build nanoscale structures and regulate complex biological systems (Stewart, 2024). RNA has ...

“A lot of these words are equivalent, or synonymous,” Grome said. “We set out to add more ingredients for building ... Specifically, the researchers eliminated two of the three stop codons that ...