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The TP53 Gene and Its Role in Cancer
Medically reviewed by Marla Anderson, MD The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for ...
Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer ...
Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.
复旦大学附属华东医院血液科近日在血液领域权威期刊Blood Cancer Journal上在线发表了题为“Decitabine with etoposide is effective in TP53 mutated myeloid tumors via ...
The team is optimizing the cancer genome analysis system to integrate it into CRC diagnosis and tailor treatments based on genetic mutations.
Researchers used mutational analysis to identify gene mutations that may drive carcinogenesis in colorectal tumors with high ...
In many cancer types, the TP53 gene is often mutated or deleted, which inactivates the tumour suppression activity of the p53 protein. However, loss of p53 tumour-suppressor activity can also ...
Within a cohort they examined, they found, first, that the subtype itself has two subtypes; and then, in one of those, called low hypodiploid ALL, 91 percent of patients carried certain variants of ...
A study released by the National Cancer Center Japan has revealed higher rates of mutations in a tumor-suppressing gene, TP53, in Japanese cancer patients compared to those in the United States ...
Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer ...