Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of glucose and metabolites activates resident macrophages in kidneys. Resident macrophages play diverse roles on ...

Tissue-resident macrophages have been associated with important and diverse biological processes such as native immunity, tissue homeostasis and angiogenesis during development and postnatally. Thus, ...

PPAR-γ is prominently expressed in activated monocytes and tissue macrophages in vivo, including the foam cells of atherosclerotic lesions 6,7. Multiple functions have been proposed for PPAR-γ ...

Research from VIB-UGent identifies lipid-associated macrophages and LAM-like Kupffer cells as critical for liver repair. The study reveals TREM2's role in clearing damaged cells and promoting recovery ...

A big thank you to Facebook for reminding you guys of my birthday. Thank you for squeezing every penny out of me last night, and now I’m broke. Thank you for the crazy night, guys.

Sending thank you for everything you have done for me messages to people who deserve your gratitude is important. You need to choose the message wisely depending on what you want to communicate. You ...

This risk has been attributed to visceral adipose tissue (vAT) expansion associated with increased proinflammatory mediators. Accumulation of CD11c + proinflammatory adipose tissue macrophages (ATM) ...

The underlying regulatory mechanisms of metabolic switching are assessed by both in vitro and in vivo studies. Conclusions Selectively modulating the ‘context’ of glycolytic macrophages in HCC tumours ...

Researchers have developed a new avenue to reprogram compromised immune cells to act against tumors. The findings highlight a potential path forward for treating late-stage tumors that have become ...

Exacerbations of these diseases are also frequently associated with bacterial and atypical bacterial infection. Alveolar macrophages are the major immune cells in the airways and are important in ...

Division of Physiological Chemistry and Metabolism, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan Laboratory of Metabolomics, RIKEN Center for Integrative ...