Ubiquitylation is a reversible post-translational modification involved in a myriad of cellular functions. A superfamily of approximately 100 ubiquitin-specific proteases, called deubiquitylating ...

An enzyme called Ubiquitin-specific peptidase 5 is a key factor in protein quality in heart muscle cells ...

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart -- an important process for maintaining heart health.

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart – an important process for maintaining heart health.

An enzyme called Ubiquitin-specific peptidase 5 is a key factor in protein quality in heart muscle cellsA disrupted protein ...

E1 enzymes facilitate conjugation of ubiquitin and ubiquitin-like proteins through adenylation ... These studies were followed by an in vivo screen in yeast that uncovered at least three critical E2 ...

Ubiquitin ligases regulate many processes in ... Dimerization is, therefore, an important regulatory mechanism." "If HACE1 no longer functions correctly in the cell or is missing altogether ...

During ubiquitination, a small protein known as ubiquitin is attached to other ... are involved in ubiquitination's diverse ...